Cell Biology Seminar

Mondays - 11:15

Room C161, IZB, Baltzerstrasse 4, 3012 Bern

ICB Seminars Fall Semester 2025

Date

Speaker

Affiliation

Talk Title

22. September, 2025

Dr. Sopie Pantalacci and Prof. Dr. Marie Sémon
(invited by Prof. Dr. Peter Meister)

LBMC / Ecole Normale Supérieure de Lyon

"What serial appendages can tell us about pleiotropy and its role in evolution"

29. September, 2025

Prof. Dr. Colinda Scheele
(Invited by Dr. Agne Frismantiene)

KU Leuven, Department of Oncology

"How breast tissue defends itself: insights into cancer protection mechanisms"

06. October, 2025

Prof. Dr. Abby Dernburg
(Invited By Prof. Dr. Peter Meister)

University of California Berkeley

"Counting to one: how live imaging revealed a mechanism for crossover patterning"

13. October, 2025

Dr. Michael Rera
(Invited by Prof. Dr. Benjamin Towbin)

Unité de Biologie Fonctionnelle et Adaptative, Paris

"Ageing is a discontinuous process"

20. October, 2025

Dr. Aneta Koseska
(Invited by Prof. Dr. Olivier Pertz)

Max Planck Institute for Neurobiology of Behavior – caesar, Bonn

"Computational capabilities of single cells"

27. October, 2025

Prof. Dr. Mark Carrington
(Invited by Prof. Dr. Eva Glünz)

University of Cambridge

"Identification of the Trypanosoma brucei gambiense genes necessary and sufficient for resistance to the human Trypanolytic Lytic Factor"

03. November, 2025

Prof. Dr. David Brückner
(Invited by Prof. Dr. Olivier Pertz)

Biozentrum Basel

“Information flow in self-organized developmental systems”

10. November, 2025

Prof. Dr. Krzysztof Gogolewski
(Invited by Dr. Maciej Dobrzynski)

University of Warsaw

"Decoding the Molecular World: From Graph-Based to Deep Learning Models and Methods"

01. December, 2025

Prof. Dr. Michel Steinmetz
(Invited by Prof. Dr. Olivier Pertz)

Paul Scherrer Institute Center for Life Sciences, Villigen

"Microtubule-mediated signaling and interactions with anticancer drugs"

08. December, 2025

Prof. Dr. Ryan Baugh
(Invited by Prof. Dr. Benjamin Towbin)

Duke University

“Adult consequences of early life starvation in the roundworm C. elegans”

Monday, November 10th, 2025 - 11:15 - Baltzerstrasse 4, Room C161

Photo of professor doctor Krzysztof Gogolewski

Prof. Dr. Krzysztof Gogolewski | University of Warsaw | "Decoding the Molecular World: From Graph-Based to Deep Learning Models and Methods"

Understanding biological complexity increasingly depends on computational models that integrate information across multiple scales, starting from genomes up to tissues. In this talk, I will present how our group develops and applies probabilistic and deep learning methods to uncover the latent logic of biological systems. I will briefly contrast our earlier work on the evolutionary history of human chromosome 2 with current efforts within the IMMUcan and SPACETIME consortia, including SpaceLet and IMMU-vis tools, which model immune–tumor interactions in spatially resolved data. I will also highlight our recent initiatives on spatiotemporal modeling of cellular signaling. Overall, I am aiming to show how modern machine learning is accelerating biomed research and enabling us to decode molecular processes with a new level of precision.

Monday, December 1st, 2025 - 11:15 - Baltzerstrasse 4, Room C161

Photo of Prof. Dr. Michel Steinmetz

Prof. Dr. Michel Steinmetz | Paul Scherrer Institute, Center for Life Scienes | "Microtubule-mediated signaling and interactions with anticancer drugs"

Proteins and their interaction networks are at the heart of life. Understanding how diverse proteins come together spatially and temporally and how their specific complexes translate into cellular functions is important to understand health and disease but represents a major challenge. Microtubules are filamentous structures fundamentally involved in diverse cellular processes ranging from cell division, motility and polarity to signaling and intracellular transport. They are also key to form centrioles of centrosomes and axonemes of cilia and flagella. Because of their important role for cell survival, the malfunctioning of the microtubule cytoskeleton is associated with several severe human pathologies including cancer and various forms of ciliopathies as well as cardiovascular, infectious and brain diseases. The Steinmetz lab uses X-ray crystallography in combination with biochemical and biophysical methods to investigate how proteins and drugs regulate the structure, function and dynamics of the microtubule cytoskeleton.

Monday, December 8th, 2025 - 11:15 - Baltzerstrasse 4, Room C161

photo of professor doctor ryan baugh

Prof. Dr. Ryan Baugh | Duke University | “Adult consequences of early life starvation in the roundworm C. elegans”

The Baugh Lab is interested in phenotypic plasticity and developmental robustness despite variable environmental conditions. They use the roundworm C. elegans to study how animals adapt to starvation over different time scales using functional genomics (bulk and single-cell) as well as statistical, quantitative, and molecular genetics. Their research questions revolve around how gene regulation and development are governed by nutrient availability, how animals acclimate to survive starvation, and the mechanisms underlying adult consequences of early life starvation. They are gaining insight into the genetic basis of natural variation among wild strains, the function of conserved tumor suppressors, epigenetic effects of starvation, and how early life experience affects adult disease.